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In enzymology, a cytidylate cyclase is an enzyme that catalyzes the chemical reaction

Hence, this enzyme has one substrate, CTP, and two products, 3',5'-cyclic CMP and diphosphate.

This enzyme belongs to the family of lyases, specifically the class of phosphorus-oxygen lyases. The systematic name of this enzyme class is CTP diphosphate-lyase. Other names in common use include 3',5'-cyclic-CMP synthase, cytidylyl cyclase, cytidyl cyclase, and CTP diphosphate-lyase.

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