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A dual therapy stent is a coronary artery stent that combines the technology of an antibody-coated stent and a drug-eluting stent. Currently, second-generation drug-eluting stents require long-term use of dual-antiplatelet therapy, which increases the risk of major bleeding occurrences in patients. Compared to drug-eluting stents, dual therapy stents have improved vessel regeneration and cell proliferation capabilities. As a result, dual therapy stents were developed to reduce the long-term need for dual-antiplatelet therapy.
The COMBO stent is the first and only dual therapy stent that addresses the challenges of vessel healing in drug-eluting stents. This stent is an anti-CD34 antibody-coated and sirolimus-eluting bioresorbable stent. The COMBO stent combines the Genous stent's endothelial cell capture technology with an antiproliferative, biodegradable sirolimus drug elution. The COMBO stent has received CE Mark approval.