The only class of immunoglobulin which is transported across the placenta is:?

Option 1 : Ig G

Concept:

• Immunoglobulin: These are the Y- shaped proteins which play a huge role in an immune response.
• They are produced when the body comes in contact with an antigen.
• An immunoglobulin test measures the level of types of antibodies in the blood.

Explanation:

• There are 5 types of heavy chain constant regions in antibodies (immunoglobulin) and according to these types, they are classified into IgG, IgM, IgA, IgD, and IgE.
• The only class of antibodies which can cross the placental barrier is the IgG antibody.
• The FcRn expressed on the surface of the syntiotrophoblast cells mediate the movement of these antibodies from the mother to the fetus.

• Ig D: These antibodies cannot cross the placental barrier.
• Ig E: These antibodies cannot cross the placental barrier.
• Ig M: These antibodies cannot cross the placental barrier.