In the First Folio edition of Shakespeare's dramas, which play was omitted?

Option 2 : Pericles

The correct answer is Pericles.

•  Pericles, Prince of Tyre is a Jacobean play written at least in part by William Shakespeare. 
• There are numerous questions over its entire authorship, as it was not included in the First Folio published in 1623.
• The originally published text of Pericles, the 1609 quarto, is clumsily written and incomprehensible and has been interpreted as a pirated text reconstructed from memory. 
• Modern textual studies suggest that the first two acts, 835 lines detailing the many voyages of Pericles, was written by a collaborator named George Wilkins, who was active as a playwright for 3-4 years between 1606 and 1610. 

•  Titus Andronicus is another play which Shakespeare wrote in collaboration. It is believed to have been written between 1588 and 1593, probably in collaboration with George Peele.  It is thought to be Shakespeare's first tragedy and is often seen as his attempt to emulate the violent and bloody revenge plays of his contemporaries. 
• In the First Folio text of 1623, the play was published under the title The Lamentable Tragedy of Titus Andronicus, based primarily on the Q3 text published for Edward White. 
• Macbeth was first printed in the First Folio of 1623 and the Folio is the only source for the text. Some scholars contend that the Folio text was abridged and rearranged from an earlier manuscript or prompt book.
• A Midsummer Night's Dream was entered into the Register of the Stationers' Company on 8 October 1600 by the bookseller Thomas Fisher, who published the first quarto edition later that year. A second quarto was printed in 1619 by William Jaggard, as part of his so-called False Folio. The play next appeared in print in the First Folio of 1623.