What can help soothe extraction pain on the bottom portion of your mouth?

Assuming you are talking about pain from tooth extraction, the dentist will prescribe any pain relieving recommendations that they feel is necessary — which often is NOT opiate medication. Many soothing medications can include acetaminophen (Tylenol) 1000 mg every eight hours alternated with Ibuprofen (Motrin) 600–800 mg every six hours as needed. (This of course, is for a healthy adult without any additional medical conditions that may cause issues or interactions with Tylenol or Motrin.) Always seek the advice of your physician/dentist/pharmacist if you have any questions or concerns relating to your condition. Lastly, swelling is common response after tooth extraction. Icing the area is often helpful in reducing swelling.