Diastat Tablet

Introduction

Diastat Tablet 25 mg is an anti-diabetic medication prescribed to help control blood sugar levels in people with type 2 diabetes. It is generally used in conjunction with diet and exercise to get the best results from the treatment.

Uses For

Diastat Tablet 25 mg is used to treat type 2 diabetes in adult patients. It is important to note that Diastat Tablet 25 mg does not take the place of regular exercise and a healthy diet. The medication should be combined with these lifestyle changes to help improve the patient's wellbeing and health.

Brand Name	Diastat
Type	Tablet
Weight	25 mg
Generic	Empagliflozin
Manufacturer	The White Horse Pharma
Available in	English বাংলা

Mechanism of Action

Diastat Tablet 25 mg works by increasing the amount of glucose excreted in the urine by blocking sodium-glucose cotransporters in the renal proximal tubule. This in turn helps to reduce the amount of glucose present in the bloodstream, improving glycemic control.

How Long Does It Take to Work?

Diastat Tablet 25 mg can start to take effect after as little as two weeks. The most significant results are seen after about 2 months. After this amount of time, the medication should be reassessed to ensure that it is still effective.

Absorption

Diastat Tablet 25 mg is rapidly absorbed following oral administration. Peak plasma concentrations of the drug are typically achieved in less than 90 minutes.

Route of Elimination

Diastat Tablet 25 mg is excreted predominantly in the urine and to a lesser degree in the feces. Only a small portion of the drug is metabolized.

Dosage

The recommended dose of Empagliflozin is 10 mg once daily, taken in the morning, with or without food. In patients tolerating Empagliflozin, the dose may be increased to 25 mg once daily. In patients with volume depletion, correcting this condition prior to initiation of Empagliflozin is recommended.

The usual starting dose for Diastat Tablet 25 mg is 10 mg once daily. The dose can be increased to 25 mg per day based on blood glucose control. The maximum dose is 25 mg per day.

Administration

Diastat Tablet 25 mg should be taken once a day with or without food. Taking the medication at the same time each day will help to ensure the desired results are achieved.

Side Effect

Common side effects of Diastat Tablet 25 mg include: nausea, diarrhea, urinary tract infections, and upper respiratory tract infections. Other side effects that may occur include increased cholesterol levels, urinary frequency, dizziness, and rash.

Toxicity

The toxic dose of Diastat Tablet 25 mg is unknown but toxic doses of other sodium-glucose cotransporter 2 (SGLT2) inhibitors have been reported in cases of accidental ingestion or overdose. Symptoms of overdose include vomiting, abdominal pain, low blood sugar levels, metabolic acidosis, fluid and electrolyte disturbances, and changes in heart rate and rhythm.

Precaution

Diastat Tablet 25 mg should be used with caution in patients with renal impairment, severe congestive heart failure, hepatic impairment, and in those with a history of ketoacidosis. Close medical supervision is also necessary in cases of dehydration and during periods of high fluid loss due to exercise.

Interaction

Diastat Tablet 25 mg can interact with certain medications such as diuretics, ACE inhibitors, angiotensin receptor blockers, corticosteroids, and thiazolidinediones. These interactions may increase or decrease the effectiveness of the Diastat Tablet 25 mg, or in rare cases may increase the risk of side effects. It is important to consult with a doctor before taking Diastat Tablet 25 mg with any other medication.

Disease Interaction

Diastat Tablet 25 mg can interact with certain diseases such as congestive heart failure, renal impairment, and hepatic impairment. Close medical supervision is necessary in these cases to ensure that the medication is taken in the safest and most effective way.

Drug Interaction

Diastat Tablet 25 mg can interact with several other medications such as ACE inhibitors, angiotensin receptor blockers, diuretics, corticosteroids, and thiazolidinediones. Careful monitoring is necessary to ensure that the drug is taken in the safest and most effective manner.

Food Interaction

Diastat Tablet 25 mg has no known food interactions. However, it is important to inform your doctor about any other medications being taken or any food allergies or intolerances in order to ensure that the drug is safe to take.

Pregnancy Use

Diastat Tablet 25 mg is generally not recommended to be taken by pregnant women. If a woman becomes pregnant while taking Diastat Tablet 25 mg, they should contact their doctor immediately.

Lactation Use

Diastat Tablet 25 mg is not recommended to be taken by women who are breastfeeding. If a woman is breastfeeding while taking the medication, she should contact her doctor to discuss alternative options.

Acute Overdose

Symptoms of acute overdose of Diastat Tablet 25 mg include vomiting, abdominal pain, low blood sugar levels, metabolic acidosis, fluid and electrolyte disturbances, and changes in heart rate and rhythm.

Contraindication

Diastat Tablet 25 mg is contraindicated for use in patients who are hypersensitive to any of the ingredients in the medication. It should also not be used in patients with type 1 diabetes.

Use Direction

Diastat Tablet 25 mg should be taken as directed by the prescribing physician. The usual dose is 10mg orally once per day. If more control is needed, the dose may be increased to 25 mg per day.

Storage Condition

Diastat Tablet 25 mg tablets should be stored in a cool, dry place away from excess heat and moisture. The medication should be kept out of the reach of children and should not be shared with other people.