Introduction

Jardiance Tablet 25 mg is an anti-diabetic medication prescribed to help control blood sugar levels in people with type 2 diabetes. It is generally used in conjunction with diet and exercise to get the best results from the treatment.

Uses For

Jardiance Tablet 25 mg is used to treat type 2 diabetes in adult patients. It is important to note that Jardiance Tablet 25 mg does not take the place of regular exercise and a healthy diet. The medication should be combined with these lifestyle changes to help improve the patient's wellbeing and health.

Brand Name Jardiance
Type Tablet
Weight 25 mg
Generic Empagliflozin
Manufacturer Radiant Pharmaceuticals Ltd.
Available in English বাংলা

Mechanism of Action

Jardiance Tablet 25 mg works by increasing the amount of glucose excreted in the urine by blocking sodium-glucose cotransporters in the renal proximal tubule. This in turn helps to reduce the amount of glucose present in the bloodstream, improving glycemic control.

How Long Does It Take to Work?

Jardiance Tablet 25 mg can start to take effect after as little as two weeks. The most significant results are seen after about 2 months. After this amount of time, the medication should be reassessed to ensure that it is still effective.

Absorption

Jardiance Tablet 25 mg is rapidly absorbed following oral administration. Peak plasma concentrations of the drug are typically achieved in less than 90 minutes.

Route of Elimination

Jardiance Tablet 25 mg is excreted predominantly in the urine and to a lesser degree in the feces. Only a small portion of the drug is metabolized.

Dosage

The recommended dose of Empagliflozin is 10 mg once daily, taken in the morning, with or without food. In patients tolerating Empagliflozin, the dose may be increased to 25 mg once daily. In patients with volume depletion, correcting this condition prior to initiation of Empagliflozin is recommended.

The usual starting dose for Jardiance Tablet 25 mg is 10 mg once daily. The dose can be increased to 25 mg per day based on blood glucose control. The maximum dose is 25 mg per day.

Administration

Jardiance Tablet 25 mg should be taken once a day with or without food. Taking the medication at the same time each day will help to ensure the desired results are achieved.

Side Effect

Common side effects of Jardiance Tablet 25 mg include: nausea, diarrhea, urinary tract infections, and upper respiratory tract infections. Other side effects that may occur include increased cholesterol levels, urinary frequency, dizziness, and rash.

Toxicity

The toxic dose of Jardiance Tablet 25 mg is unknown but toxic doses of other sodium-glucose cotransporter 2 (SGLT2) inhibitors have been reported in cases of accidental ingestion or overdose. Symptoms of overdose include vomiting, abdominal pain, low blood sugar levels, metabolic acidosis, fluid and electrolyte disturbances, and changes in heart rate and rhythm.

Precaution

Jardiance Tablet 25 mg should be used with caution in patients with renal impairment, severe congestive heart failure, hepatic impairment, and in those with a history of ketoacidosis. Close medical supervision is also necessary in cases of dehydration and during periods of high fluid loss due to exercise.

Interaction

Jardiance Tablet 25 mg can interact with certain medications such as diuretics, ACE inhibitors, angiotensin receptor blockers, corticosteroids, and thiazolidinediones. These interactions may increase or decrease the effectiveness of the Jardiance Tablet 25 mg, or in rare cases may increase the risk of side effects. It is important to consult with a doctor before taking Jardiance Tablet 25 mg with any other medication.

Disease Interaction

Jardiance Tablet 25 mg can interact with certain diseases such as congestive heart failure, renal impairment, and hepatic impairment. Close medical supervision is necessary in these cases to ensure that the medication is taken in the safest and most effective way.

Drug Interaction

Jardiance Tablet 25 mg can interact with several other medications such as ACE inhibitors, angiotensin receptor blockers, diuretics, corticosteroids, and thiazolidinediones. Careful monitoring is necessary to ensure that the drug is taken in the safest and most effective manner.

Food Interaction

Jardiance Tablet 25 mg has no known food interactions. However, it is important to inform your doctor about any other medications being taken or any food allergies or intolerances in order to ensure that the drug is safe to take.

Pregnancy Use

Jardiance Tablet 25 mg is generally not recommended to be taken by pregnant women. If a woman becomes pregnant while taking Jardiance Tablet 25 mg, they should contact their doctor immediately.

Lactation Use

Jardiance Tablet 25 mg is not recommended to be taken by women who are breastfeeding. If a woman is breastfeeding while taking the medication, she should contact her doctor to discuss alternative options.

Acute Overdose

Symptoms of acute overdose of Jardiance Tablet 25 mg include vomiting, abdominal pain, low blood sugar levels, metabolic acidosis, fluid and electrolyte disturbances, and changes in heart rate and rhythm.

Contraindication

Jardiance Tablet 25 mg is contraindicated for use in patients who are hypersensitive to any of the ingredients in the medication. It should also not be used in patients with type 1 diabetes.

Use Direction

Jardiance Tablet 25 mg should be taken as directed by the prescribing physician. The usual dose is 10mg orally once per day. If more control is needed, the dose may be increased to 25 mg per day.

Storage Condition

Jardiance Tablet 25 mg tablets should be stored in a cool, dry place away from excess heat and moisture. The medication should be kept out of the reach of children and should not be shared with other people.

Volume of Distribution

Jardiance Tablet 25 mg has a volume of distribution of approximately 2.3 L/kg.

Half Life

The half-life of Jardiance Tablet 25 mg is approximately 17 to 20 hours.

Clearance

Jardiance Tablet 25 mg is eliminated primarily by renal excretion. It has an oral clearance of approximately 115 mL/min.

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Uses

Some Frequently Asked Questions About Jardiance Tablet 25 mg

*** Taking medicines without doctor's advice can cause long-term problems.
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