Ceftiben Capsule

Ceftibuten is a third-generation cephalosporin antibiotic that is orally-administered. It is typically used to treat acute bacterial exacerbations of chronic bronchitis (ABECB), acute bacterial otitis media, pharyngitis, and tonsilitis.

Ceftibuten is a third-generation cephalosporin antibiotic commonly used in the treatment of acute bacterial exacerbations of chronic bronchitis (ABECB), acute bacterial otitis media, pharyngitis, and tonsillitis.

Indicated for the treatment of acute bacterial exacerbations of chronic bronchitis (ABECB), acute bacterial otitis media, pharyngitis, and tonsilitis.

• Acute Bacterial Exacerbation of Chronic Bronchitis (ABECB)
• Acute Otitis Media
• Acute Sinusitis
• Acute Tracheobronchitis
• Bacterial Infections
• Bacterial Pneumonia
• Lower Respiratory Tract Infection (LRTI)
• Lower Respiratory Tract Infection (LRTI) caused by susceptible bacteria
• Pharyngitis
• Skin and Soft Tissue Infections
• Streptococcal Pharyngitis
• Streptococcal tonsillitis
• Superinfection bacterial
• Tonsillitis
• Upper Respiratory Tract Infection
• Upper Respiratory Tract Infection caused by susceptible bacteria
• Urinary Tract Infection caused by susceptible bacteria
• Bacterial otitis media
• Uncomplicated Lower Respiratory Tract Infection (LRTI)
• Uncomplicated Upper Respiratory Tract Infection
• Uncomplicated Urethritis gonococcal

Ceftibuten is an antibiotic with bactericidal actions.

Ceftibuten exerts its bactericidal action by binding to essential target proteins of the bacterial cell wall. This binding leads to inhibition of cell-wall synthesis.

Rapidly absorbed following oral administration.

• 0.21 L/kg [adult subjects]
• 0.5 L/kg [fasting pediatric patients]

Ceftibuten is 65% bound to plasma proteins. The protein binding is independent of plasma ceftibuten concentration.

Ceftibuten is excreted in the urine; 95% of the administered radioactivity was recovered either in urine or feces.

Overdosage of cephalosporins can cause cerebral irritation leading to convulsions.

• Take separate from meals. Take ceftibuten oral suspension at least one hour after eating, or two hours before eating.
• Take with or without food. Separating the administration of ceftibuten from food is not required for ceftibuten capsules because the impact of food on bioavailability is less significant.

• Adult Dosage: 400 mg orally every 24 hours for 10 days
• Pediatric Dosage: >6 months: 9 mg/kg/day (maximum 400 mg) every 24 hours for 10 days

• Adult Dosage: 400 mg orally every 24 hours for 10 days
• Pediatric Dosage: >6 months: 9 mg/kg/day (maximum 400 mg) every 24 hours for 10 days

• Adult Dosage: 400 mg orally every 24 hours for 10 days
• Pediatric Dosage: >12 years: 400 mg orally every 24 hours for 10 days

• Adult Dosage: 400 mg orally every 24 hours for 7 days
• Pediatric Dosage: >12 years: 400 mg orally every 24 hours for 7 days

• Adult Dosage: 200 mg orally every 12 hours for 7 to 14 days
• Pediatric Dosage: >12 years: 200 mg orally every 12 hours for 7 to 14 days

• Adult Dosage: 400 mg orally every 24 hours for 10 to 14 days
• Pediatric Dosage: >12 years: 400 mg orally every 24 hours for 10 to 14 days

• Adult Dosage: 400 mg orally every 24 hours for 10 days
• Pediatric Dosage: >6 months: 9 mg/kg/day (maximum 400 mg) every 24 hours for 10 days