Almitan Tablet 6.25 mg

Almitan Tablet 6.25 mg is a serotonin receptor agonist (also known as a “triptan”), and the only approved triptan to treat symptomatic acute migraine headaches in adults. It is an oral prescription medication and it is available as an oral tablet in 6.25 mg and 12.5 mg dosages. It works by stimulating serotonin receptor sites in the brain and helps reduce pain, nausea, and sensitivity to light and sound associated with migraine attacks.

Uses for Almitan Tablet 6.25 mg

Almitan Tablet 6.25 mg is used for the treatment of acute migraine headaches in adults. It works by stimulating serotonin receptor sites in the brain to reduce the symptoms of migraine, including pain, nausea, and sensitivity to light and sound.

Brand Name Almitan
Type Tablet
Weight 6.25 mg
Generic Almotriptan
Manufacturer Opsonin Pharma Ltd.
Available in English বাংলা

Mechanism of Action

Almitan Tablet 6.25 mg works by targeting serotonin receptor sites in the brain. It is believed that this action helps reduce the pain, nausea, and sensitivity to light and sound associated with migraine attacks. Almitan Tablet 6.25 mg helps increase the levels of serotonin in the brain and can help reduce the intensity and duration of migraine headache attacks.

How long does it take to work?

Almitan Tablet 6.25 mg typically takes approximately 30 minutes to reach its peak effect in the body. It is recommended to take the medication as soon as possible after the onset of migraine symptoms. If no relief is obtained after taking the first dose, a second dose may be taken at least 2 hours later.

Absorption

Almitan Tablet 6.25 mg is rapidly absorbed from the gastrointestinal (GI) tract. It reaches peak plasma concentrations after approximately 75 minutes.

Route of Elimination

Almitan Tablet 6.25 mg is metabolized by the liver and is primarily excreted in the urine as metabolites.

Dosage

Acute Treatment of Migraine Attacks: The recommended dose of Almotriptan in adults and adolescents age 12 to 17 years is 6.25 mg to 12.5 mg, with the 12.5 mg dose tending to be a more effective dose in adults. If the headache is relieved after the initial almotriptan malate dose but returns, the dose may be repeated after 2 hours. The maximum daily dose should not exceed 25 mg. The safety of treating an average of more than four migraines in a 30-day period has not been established.

Hepatic Impairment: The recommended starting dose of almotriptan malate in patients with hepatic impairment is 6.25 mg. The maximum daily dose should not exceed 12.5 mg over a 24-hour period

Renal Impairment: The recommended starting dose of almotriptan malate in patients with severe renal impairment is 6.25 mg. The maximum daily dose should not exceed 12.5 mg over a 24-hour period

The recommended dose of Almitan Tablet 6.25 mg is one 6.25 mg or 12.5 mg tablet. Do not take more than one 12.5 mg tablet in 24 hours. Do not take more than two 6.25 mg tablets in 24 hours. Do not take this medication if you have taken any of the other triptans (eg, sumatriptan, naratriptan) within the last 24 hours.

Administration

Almitan Tablet 6.25 mg may be taken with or without food. Drink a full glass of water after taking this medication.  

Side Effects

Common side effects of Almitan Tablet 6.25 mg include nausea, drowsiness, dizziness, dry mouth, and weakness. Serious side effects may include chest discomfort or pain, tightness or heavy feeling, rapid or irregular heartbeat, numbness or tingling, mouth or throat tightness, and confusion.

Toxicity

Almitan Tablet 6.25 mg is not known to be toxic when taken as prescribed. Taking more than the recommended dose can cause serious side effects, and should be avoided.

Precautions

Before taking Almitan Tablet 6.25 mg, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. Before using this medication, tell your doctor or pharmacist your medical history, especially of heart problems, stroke, blood circulation problems, ischemic bowel disease, kidney problems, and liver problems.

Interactions

Almitan Tablet 6.25 mg can interact with certain other medications, including tryptophan, MAO inhibitors, type 5 phosphodiesterase inhibitors, other serotonin receptor agonists, certain antibiotics, and nonsteroidal anti-inflammatory drugs (NSAIDs). Tell your doctor or pharmacist about any medications you are taking or plan to take before taking this medication. Do not start or stop any medications without talking to your doctor first.

Disease Interactions

Almitan Tablet 6.25 mg may not be appropriate for use in people with certain disease conditions. Tell your doctor if you have any of the following conditions before taking Almitan Tablet 6.25 mg: stroke, ischemic bowel disease, kidney or liver problems, or those with a history of heart disease.

Drug Interactions

Almitan Tablet 6.25 mg may interact with certain types of medications. Tell your doctor or pharmacist all medications you are taking or plan to take before taking this medication. Do not start or stop any medications without talking to your doctor first.

Food Interactions

Almitan Tablet 6.25 mg may interact with certain foods or beverages. It is recommended to avoid consuming alcohol while taking Almitan Tablet 6.25 mg and to avoid eating certain foods that may cause or intensify migraine symptoms. Speak to your doctor or pharmacist to learn more.

Pregnancy Use

It is not known if Almitan Tablet 6.25 mg is safe to use during pregnancy. Speak to your doctor before using this medication if you are pregnant or could become pregnant.

Lactation Use

It is not known if Almitan Tablet 6.25 mg is safe to use while breastfeeding. Speak to your doctor before using this medication if you are nursing.

Acute Overdose

Almitan Tablet 6.25 mg may cause serious side effects if taken in larger than prescribed doses. Seek immediate medical attention if you believe you have overdosed on Almitan Tablet 6.25 mg.

Contraindication

Almitan Tablet 6.25 mg is contraindicated in people with certain medical conditions and in those taking certain medications. Speak to your doctor before taking this medication if you have or have had any heart problems, blood circulation problems, ischemic bowel disease, kidney problems, or liver problems. Almitan Tablet 6.25 mg is also contraindicated in people who have taken certain types of medications, including tryptophan, MAO inhibitors, type 5 phosphodiesterase inhibitors, other serotonin receptor agonists, and certain antibiotics or NSAIDs.

Use Directions

Almitan Tablet 6.25 mg should be taken as soon as possible after the onset of migraine symptoms. The recommended dose for adults is one 6.25 mg or 12.5 mg tablet. Do not take more than one 12.5 mg tablet in 24 hours and do not take more than two 6.25 mg tablets in 24 hours. Drink a full glass of water after taking this medication. Almitan Tablet 6.25 mg can be taken with or without food.

Storage Conditions

Almitan Tablet 6.25 mg should be stored in a tightly sealed container at room temperature. Keep this medication away from moisture and out of the reach of children.

Volume of Distribution

Almitan Tablet 6.25 mg has a relatively small volume of distribution in the body. The estimated volume of distribution is 37.3 L.

Half Life

The estimated half-life of Almitan Tablet 6.25 mg is approximately 3 hours.

Clearance

Almitan Tablet 6.25 mg is metabolized by the liver and is primarily excreted in the urine as metabolites. The estimated clearance is 22.3 L/h.

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*** Taking medicines without doctor's advice can cause long-term problems.
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