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Doctors Medicines MCQs Q&A

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With reference to a three-parent baby, consider the following statements: 1. The healthy nuclear DNA is removed from the patient egg cell, leaving behind faulty mitochondrial DNA. 2. Patient nuclear DNA will be transplanted to a donor’s egg with healthy mitochondrial DNA. Which of the statements given above is/are correct?
Steps of Recombinant DNA technology are given below.
1. Identification and isolation of the genetic material.
2. Fragmentation of DNA.
3. Obtaining the foreign gene product.
4. Downstream processing.
5. Ligation of DNA fragmentation into the vector.
6. Isolation of desired DNA fragments.
7. Amplification of gene of interest.
8. Transfer of Recombinant DNA into the host cell/organism.
The correct sequence of steps is
In the context of hereditary diseases, consider the following statements : 1. Passing on mitochondrial diseases from parent to child can be prevented by mitochondrial replacement therapy either before or after in vitro fertilization of the egg. 2. A child inherits mitochondrial diseases entirely from the mother and not from the father. Which of the statements given above is/are correct?  
Consider the following statements regarding DNA replication and choose the correct answer:
1. The very first requirement of DNA synthesis is the presence of a template or plan along which the new strand is to be constructed
2. The second requirement is of a DNA-dependent-DNA polymerase or simply DNA polymerase enzyme
3. A DNA Pol cannot join two free nucleotides; one of them must be anchored by hydrogen bonds to a DNA strand
4. Replication takes place bidirectionally
Consider the following statements regarding the DNA-mediated gene transfer and choose the correct answer:
1. DNA fragments carrying the gene to be transferred are mixed with a carrier DNA
2. They are then precipitated out with a calcium phosphate buffer
3. The precipitate is used to transform target cells
4. The Ca-precipitated DNA enters the cell by exocytosis
Which of the following statements about gene therapy are correct?
P. Affected individuals, but not their progeny, can be cured through germline gene therapy.
Q. Affected individuals, as well as their progeny, can be cured through germline gene therapy.
R. Affected individuals, but not their progeny, can be cured through somatic gene therapy.
S. Affected individuals, as well as their progeny, can be cured through somatic gene therapy.
Which of the following statements is/are correct? 1. Gene Editing deals with inserting genes from other organism while Gene Modification deals with altering genes that exists already within body. 2. Gene Modification process is time consuming while Gene editing is faster. Select the correct answer using the code given below.
Consider the following statements Gene Therapy 1. Gene therapy is a medical field which focuses on the genetic modification of cells to produce a therapeutic effect. 2. CRISPR - 9 is a kind of gene therapy tool used in gene editing technology. Select the correct answer using the code given below:
In Reverse-genetics analysis of gene function– Even though a particular gene may be _____ ortholog of a gene of known function in another organism, that gene may be acquired by a _____ function.
Consider the following statements.
1. Golden rice is vitamin A rich.
2. Replacement of faulty gene by normal gene is called gene therapy.
3. Transgenic organism carrying introduced foreign gene also called genetically modified organism.
Which of the statements given above are true?