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Doctors Medicines MCQs Q&A

With reference to a three-parent baby, consider the following statements: 1. The healthy nuclear DNA is removed from the patient egg cell, leaving behind faulty mitochondrial DNA. 2. Patient nuclear DNA will be transplanted to a donor’s egg with healthy mitochondrial DNA. Which of the statements given above is/are correct?

With reference to a three-parent baby, consider the following statements: 1. The healthy nuclear DNA is removed from the patient egg cell, leaving behind faulty mitochondrial DNA. 2. Patient nuclear DNA will be transplanted to a donor’s egg with healthy mitochondrial DNA. Which of the statements given above is/are correct? Correct Answer Both 1 and 2

The correct answer is Both 1 and 2

Key Points

  • Three-parent baby:
    • In simple words when a baby is born from the DNAs of three people, then we generally call it a three-parent- baby.
    • The first three-parent baby was born recently in the USA with the help of a technique.
    • The technique replaces a small amount of faulty DNA in a mother’s egg with healthy DNA from a second woman.
    • This results in the baby inheriting genes from two mothers and one father.
    • The idea is to prohibit certain genetic diseases from being passed on to children.
    • The technique which was used in achieving this landmark in the history of medical science is known as Spindle transfer.
    • This technique is explained in detail below: 
      • The healthy nuclear DNA is removed from the patient’s egg cell, leaving behind faulty mitochondrial DNA. Hence, statement 1 is correct.
      • The patient’s nuclear DNA will be transplanted to the donor’s egg with healthy mitochondrial DNA. Hence, statement 2 is correct.
        • Therefore by replacing the dysfunctional mitochondria carried by a woman who wishes to conceive a child with the healthy mitochondria of a donor.
      • The Egg is then fertilized with the partner’s sperm through In Vitro Fertilization.
      • The embryo thus created is one technically cleansed of the mutated mitochondrial DNA that the mother originally carried.
      • The reconstructed egg cell is fertilized with sperm in the lab and implanted into the mother thus embryo will have three genetic parents.

Related Questions

Consider the following statements: 1. The chain reaction process is used in nuclear bombs to release a vast amount of energy, but in nuclear reactors, there is no chain reaction. 2. In a nuclear reactor, the reaction is controlled, while in nuclear bombs, the reaction is uncontrolled. 3. In a nuclear reactor, all operating reactors are ‘critical’, while there is no question of ‘criticality’ in case of a nuclear bomb. 4. Nuclear reactors do not use moderators, while nuclear bombs use them. Which of the above statements about operational principles of a nuclear reactor and a nuclear bomb is / are correct?
Consider the following statements.
1. The chain reaction process is used in nuclear bombs to release a vast amount of energy, but in nuclear reactors, there is no chain reaction.
2. In a nuclear reactor, the reaction is controlled, while in nuclear bombs, the reaction is uncontrolled.
3. In a nuclear reactor, all operating reactors are 'critical', while there is no question of 'critically' in case of a nuclear bomb.
4. Nuclear reactors do not use moderators, while nuclear bombs use them.
Which of the above statements about operational principles of a nuclear reactor and a nuclear bomb is/are correct?
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