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Thermal death of microorganisms in the liquid medium follows first order kinetics. If the initial cell concentration in the fermentation medium is 108 cells mL-1 and the final acceptable contamination level is 10-3 cells, for how long should 1 m3 medium be treated at temperature of 120°C (thermal deactivation rate constant = 0.23 min-1) to achieve acceptable load?

Thermal death of microorganisms in the liquid medium follows first order kinetics. If the initial cell concentration in the fermentation medium is 108 cells mL-1 and the final acceptable contamination level is 10-3 cells, for how long should 1 m3 medium be treated at temperature of 120°C (thermal deactivation rate constant = 0.23 min-1) to achieve acceptable load? Correct Answer 110 min

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