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Karl Thiersch was a german surgeon in Munich. He attempted to grow skin cells into granulation wounds. While doing so, he discovered the importance of granulation tissue in the process of wound healing in 1874. In which stage of wound healing does granulation occur?

Karl Thiersch was a german surgeon in Munich. He attempted to grow skin cells into granulation wounds. While doing so, he discovered the importance of granulation tissue in the process of wound healing in 1874. In which stage of wound healing does granulation occur? Correct Answer Inflammatory Phase

There are four phases in wound healing namely Hemostasis (1st phase), Proliferative (2nd phase), Inflammatory (3rd phase) and Maturation (4th phase) phases. As soon as a person gets hurt, the emergency system of the body sends various signals to the immune system asking for help in stopping blood flow from increasing, this is done by forming a dam like blockage. In the 2nd phase neutrophils (a kind of WBCs) enter the wound in order to sanitize the wound by killing bacteria and eradicating debris. The in the 3rd phase actual wound healing process starts by formation of new connective tissue called granulation tissue, this is followed by covering of wound with epithelia. In the 4th phase the newly formed tissue gains strength and flexibility lost due to the wound.

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