Which of the following factor does NOT contribute for the development of eosinophils for regulating the Innate Immune response?
Which of the following factor does NOT contribute for the development of eosinophils for regulating the Innate Immune response? Correct Answer IL-2
Eosinophils are produced in the bone marrow from pluripotent stem cells, which first differentiate into a precursor for basophils and eosinophils and then differentiate into an eosinophilic lineage. IL-3, IL-5, and GM-CSF are particularly important in regulating the eosinophils development. Out of these three cytokines, IL-5 is the most specific for the eosinophilic lineage and is responsible for the selective differentiation and release of eosinophils from the bone marrow into the peripheral circulation. IL-5 plays a critical role in the eosinophils production.
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Feb 20, 2025