Bissoy.com
Doctors Medicines MCQs Q&A

Which of the following are the earliest immune cells to encounter antigen at the site of injury?

Which of the following are the earliest immune cells to encounter antigen at the site of injury? Correct Answer Macrophages

Macrophages are some of the earliest immune cells to encounter antigen at sites of infection or injury. The response to antigenic stimulus is context-dependent but production of inflammatory cytokines is one of the most important function of these cells in the early stages of inflammation. For example, in the case of atherosclerosis, macrophages that infiltrate plaque take up oxidized low-density lipoprotein (ox-LDL) particles and are activated, including upregulation of antigen-presentation genes and increased production of inflammatory cytokines. 

Related Questions

Which of the following statement(s) is/are CORRECT for antigen activated effector T cells?
P. CD4+ cells make contact with macrophages and stimulate their microbicidal activity.
Q. CD4+ cells make contact with B cells and stimulate them to differentiate into plasma cells.
R. CD8+ cells make contact with B cells and stimulate them to differentiate into plasma cells.
S. CD8+ cells make contact with virus infected cells and kill them.
Which of the following statement is correct about antigen? Statement 1: The job of attacking target cells—either cells that have been infected by viruses or cells that have been distorted by cancer—is left to T cells or other immune cells. Statement 2: Antibodies ambush antigens circulating the bloodstream.
Which of the following statements about immune response are correct?
P. T cells are activated by antigen-presenting cells.
Q. Foreign peptides are not presented to helper T cells by class II MHC proteins.
R. Dendritic cells are referred to as professional antigenpresenting cells.
Which of the following is not a feature of secondary immune respone to an antigen when compared to the first immune response to the same antigen?
In the question two statements are given, followed by two conclusions, I and II. Read all the conclusions and then decide which of the given conclusions logically follow/s from the given statements. Statements: All white blood cells are red blood cells. Some blood cells are red blood cells. Conclusions: I. All blood cells are red blood cells, is a possibility. II. Some red blood cells are not blood cells.
In the following question, sentences of a paragraph have been jumbled and labelled as A, B, C, and D. You are required to rearrange the jumbled sentences of the paragraph and mark your response accordingly by selecting the correct option. A: Any foreign substance in your body that makes the immune system attack it, is called an antigen. B: It is called the immune system and it knows when there is something inside your body that should not be there. C: Therefore this special system protects you from illness and diseases caused by antigens. D: You have your own little army of cells inside you, always fighting to keep you healthy.
Consider the following statements regarding ‘Embryonic Stem (ES) cells: 1. These cells are derived from eggs fertilized in a woman's body. 2. The Embryonic cells are pluripotent. 3. The cells derived from ES cells can be used to replace/restore tissues that have been damaged by disease or an injury. Which of the following statement is/ are correct?
A B cell activates by its first encounter with an antigen called _______ antigen.
Which set of the following events occurs during the elongation step of translation?
P. Attachment of mRNA with the smaller subunit of ribosome
Q. Loading of correct aminoacyl-tRNA into the A site.
R. Formation of a peptide bond between the amino acyl-tRNA in the A site and the peptide chain that is attached to the peptidyl-tRNA in the P site.
S. Dissociation of the ribosomal subunits.
T. Translocation of peptidyl-tRNA from the A site to the P site of the ribosome.
When compared to the first immune response to the same antigen, which of the following is not a hallmark of the secondary immune response?