In the germinal centres (GCs) which cells undergo Tfh-dependent proliferation?
In the germinal centres (GCs) which cells undergo Tfh-dependent proliferation? Correct Answer B cells
In the GCs, B cells undergo Tfh-dependent proliferation as well as somatic hypermutations (SMH) in order to participate in secondary responses for activation in presence of humoral antibody. This is accompanied by class-switch recombination (CSR) and immune maturation through selection of higher affinity clones.
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Feb 20, 2025