In humans, how many subclasses of IgG are known and which of the following are they?
In humans, how many subclasses of IgG are known and which of the following are they? Correct Answer 4 subclasses – IgG1, IgG2, IgG3, IgG4
In humans, four different IgG subclasses are known. They are IgG1, IgG2, IgG3 and IgG4. These subclasses differ in amino acid sequence, which influences their capacity to interact with certain classes of FcγRs and complement components. The serum abundance of the four subclasses (from IgG1 to IgG4) is 60%, 32%, 4% and 4% respectively.
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Feb 20, 2025