Exogenous antigens are processed and presented by which cells?
Exogenous antigens are processed and presented by which cells? Correct Answer Antigen presenting cells
Exogenous antigens which are associated with MHC class II molecules activate the helper CD4+ T cells but the entire processing and presentation pathway is carried out by the Antigen Presenting Cells. These cells are also designated as APCs. APCs internalize antigens by phagocytosis or endocytosis. APCs are very important for adaptive immune responses as the functioning of helper T cells is totally dependent on APCs. This means that even if antigen-peptide-MHC class II complex activates the helper T cells, they won’t be regulated unless they come in contact with APCs.
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Feb 20, 2025