Bissoy.com
Doctors Medicines MCQs Q&A

Which of the following first binds to the NLS protein sequence?

Which of the following first binds to the NLS protein sequence? Correct Answer Importin-alpha

The molecules that contain Nucleus Localization Signal (NLS) sequence, are immediately ushered into the nucleus through nucleopore. The first step of this transport involves binding of importin-alpha to the NLS sequence, which then acts as a bridge for the attachment of importin-beta.

Related Questions

Phytase, an enzyme produced by Aspergillus niger can be adsorbed on microcrystalline cellulose powder (MCCP). The adsorption follows a Langmuir isotherm and the maximum concentration of the protein that can be obtained on the adsorbent is 70 mg cm-1. At a concentration of 50 mg L-1 of protein in the solution, the concentration of protein on the adsorbent reaches 35 mg cm-1. It is desired to recover 90% of the protein from 1.5 liter of the cell free culture filtrate containing 220 mg L-1 protein by addition of MCCP to the solution. The concentration of the protein adsorbed on the solid at equilibrium will be:
Directions : In each of the following questions a statement is given, followed by two conclusions. Give answer :

Statements : About 50 per cent of the animal by-products - hair, skin, horns etc. is edible protein. American chemists have developed a method of isolating 45 per cent of this protein. They used an enzyme developed in Japan to break down soya protein.

Conclusions :
I. Americans have not been able to develop enzymes.
II. Animal by-products protein has the same composition as soya protein.
Which of the following statements are CORRECT when a protein sequence database is searched using the BLAST algorithm?
P. A larger E-value indicates higher sequence similarity.
Q. E-value -10 indicates sequence homology.
R. A higher BLAST score indicates higher sequence similarity.
S. E-value > 10-10 indicates sequence homology.
Order the following events observed during muscle contraction in the correct sequence
1. The sarcomere shortens
2. ATP is hydrolyzed
3. Ca2+ binds to troponin
4. ATP binds to myosin
5. Mosin contracts F-actin
6. F-actin moves
7. Tropomyosin moves
8. Ca2+ is released from the sarcoplasmic reticulum
In protein/domain analysis, each protein in the predicted proteome is again used as a query of a curated protein sequence database such as ____ in order to locate similar domains and sequences. To find orthologs, very low E value scores (E<10<20) for the alignment score and an alignment that includes 60–80% of the query sequence are generally required in order to avoid matches to paralogs.
The upstream sequence where the σ protein binds constitutes the promoter sequence.
Shine Dalgamo sequence present on mRNA in case of prokaryotes plays as important role in protein synthesis. This sequence binds with . . . . . . . . during translation initiation
Select the segment of the sentence that contains the grammatical error. If there is no error, mark 'No error'. The researchers believe that they are the first to observe(a)/ when a particular protein made by the rabies virus binds to a critical cellular(b)/ protein known as Stat1, halting key parts of the immune response. (c)/ No error (d)/
Consider the following proteins: I. Chromo Protein  II. Peptone  III. Proteinase  Considering that there are three types of proteins namely Simple Protein, Conjugated Protein, and Derived Protein, which among the above is the odd one out with respect to the types mentioned above?
Protein A will fold into its native state only when protein B is also present in the solution. However, protein B can fold itself into native confirmation without the presence of protein A. Which of the following is true?