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Duplication of Vermillion eye colour gene leads to the expression of the mutant phenotype. Which of the following can lead to normal phenotype with this duplication present?

Duplication of Vermillion eye colour gene leads to the expression of the mutant phenotype. Which of the following can lead to normal phenotype with this duplication present? Correct Answer Duplication of normal eye colour gene

Duplication in normal eye colour gene would balance the mutant gene product and lead to expression of wild type phenotype. Reverse tandem duplication will only create more copies of mutant making phenotype worse, also deletion of both genes will cause imbalance. Translocation makes no difference in expression unless it’s beside a heterochromatin.

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The human eye is a complex part of the body that is used for seeing. Eyes enable people to perform daily tasks and to learn about the world that surrounds them. Sight, or vision, is a rapidly occurring process that involves continuous interaction between the eye, the nervous system, and the brain. When someone looks at an object, what he really sees is the light reflected from the object. This reflected light passes through the lens and falls on the retina of the eye. Here the light induces nerve impulses that travel through the optic nerve to the brain and then over other nerves to muscles and glands.
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