There was little degree of success in docking an antibody-antigen complex in the second challenge for the protein-protein docking evaluation.
There was little degree of success in docking an antibody-antigen complex in the second challenge for the protein-protein docking evaluation. Correct Answer True
This may be because modeling molecular recognition is in general more difficult in antibody-antigen than protein-inhibitor systems. In the protein-ligand docking challenge at CASP2 there was generally a good level of success, however, again certain targets proved to be problematic.
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Feb 20, 2025