Most vertebrate genes use __________ as the translation start codon and have a uniquely conserved flanking sequence call a Kozak sequence (CCGCCATGG).
Most vertebrate genes use __________ as the translation start codon and have a uniquely conserved flanking sequence call a Kozak sequence (CCGCCATGG). Correct Answer ATG
In addition, most of these genes have a high density of CG dinucleotides near the transcription start site. This region is referred to as a CpG island (p refers to the phosphodiester bond connecting the two nucleotides), which helps to identify the transcription initiation site of a eukaryotic gene. The poly-A signal can also help locate the final coding sequence.
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Feb 20, 2025