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If the base pair is adjacent to loops or bulges, the neighboring loops and bulges tend to ___________ the base-pair formation.

If the base pair is adjacent to loops or bulges, the neighboring loops and bulges tend to ___________ the base-pair formation. Correct Answer destabilize

This is because there is a loss of entropy when the ends of the helical structure are constrained by unpaired loop residues. The destabilizing force to a helical structure also depends on the types of loops nearby.

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