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A problem exists when comparing _____ sequences using the dot matrix method, namely, the _______

A problem exists when comparing _____ sequences using the dot matrix method, namely, the _______ Correct Answer large, high noise level

In most dot plots, dots are plotted all over the graph obscuring identification of the true alignment. For DNA sequences, the problem is particularly acute because there are only four possible characters in DNA and each residue therefore has a one-in-four chance of matching a residue in another sequence.

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