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The charging of tRNATyr with tyrosine is a single-stage reaction.

The charging of tRNATyr with tyrosine is a single-stage reaction. Correct Answer False

The above statement is false. The charging of tRNATyr with tyrosine is a two-stage reaction. The tyrosine is first activated at its carboxyl group with ATP to form tyrosyl adenylate. Subsequently, the adenylate is attacked by the 2’ or 3’ hydroxyl of the tRNA to give tyrosyl-tRNATyr.

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