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Removing which of the following enzyme cleavage site impedes the A2 dissociation?

Removing which of the following enzyme cleavage site impedes the A2 dissociation? Correct Answer Thrombin

Removing the thrombin cleavage site impedes the A2 dissociation. This removal of thrombin cleavage site R740 and R1649 in a B domain truncated FVIII causes the A2 domain to remain covalently bonded through the peptide chain to the A3 domain. Removal of furin cleavage site does not impede the A2 dissociation.

Related Questions

Which set of the following events occurs during the elongation step of translation?
P. Attachment of mRNA with the smaller subunit of ribosome
Q. Loading of correct aminoacyl-tRNA into the A site.
R. Formation of a peptide bond between the amino acyl-tRNA in the A site and the peptide chain that is attached to the peptidyl-tRNA in the P site.
S. Dissociation of the ribosomal subunits.
T. Translocation of peptidyl-tRNA from the A site to the P site of the ribosome.
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