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Excess of which of the following in water leads to pigmentation of the skin, melanosis, and excessive keratosis?

Excess of which of the following in water leads to pigmentation of the skin, melanosis, and excessive keratosis? Correct Answer Arsenic

  • The first visible symptoms caused by exposure to high Arsenic concentrations in drinking water are abnormal black-brown skin pigmentation known as melanosis and symmetrically- distributed, multiple, small elevated lesions of palms and soles known as keratosis.

Additional Information

  • Melanosis:
    • Melanosis are melanin-producing cells located in the stratum basale of the skin's epidermis, the middle layer of the eye, the inner ear, meninges, bones, and heart.
    • Melanin is the pigment primarily responsible for skin colour.
    • Through a process, called melanogenesis, these cells produce melanin.
    • This melanogenesis leads to a long-lasting pigmentation of the skin.

Related Questions

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