A newborn is presented with a bloated abdomen shortly after birth with passing of less meconium. A full thickness biopsy of the rectum was carried out. Which one of the following rectal biopsy findings is most likely to be present?
A newborn is presented with a bloated abdomen shortly after birth with passing of less meconium. A full thickness biopsy of the rectum was carried out. Which one of the following rectal biopsy findings is most likely to be present? Correct Answer Lack of ganglion cells
Concept-
- The failure of passing meconium in first 24 hours may be a sign of medical condition such as intestinal obstruction.
- The baby passes stool the meconium is passes out of their body
Stimulate the baby to bowel’s by doing the following:
- Bend their knees towards their chest.
- Gently massage their abdomen.
- Give him warm bath for relax muscles.
Explanation-
- The absence of ganglion cell leaves the affected portion of intestine paralyzed and unable to propagate stool.
- Hirschsprung disease is a birth defect. This disorder is characterized by the absence of ganglion cell
- The absence of ganglion cell causes the muscles in the bowel to lose their ability to move stool through intestine.
Additional Information
- Muscular propria thickened – thickened muscular propria was define as being present when width of muscular interna and externa of small intestine.
- Hyalinisation of muscular coat - a condition in which normal tissue deteriorates into a homogenous translucent material.
- Fibrosis of submucosa – fibrosis submucosa characterized by abnormal collagen deposition.it is precancerous disorder and transform into malignant
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Feb 20, 2025