Consider the following statements related to Acute Encephalitis Syndrome. 1. Acute encephalitis syndrome is a severe case of encephalitis transmitted by mosquitoes and is characterized by high fever and inflammation of the brain. 2. The disease does not affect children and young adults. 3. Japanese encephalitis virus (JEV) is the major cause of AES in India. Which of the above statements is/are correct?
Consider the following statements related to Acute Encephalitis Syndrome. 1. Acute encephalitis syndrome is a severe case of encephalitis transmitted by mosquitoes and is characterized by high fever and inflammation of the brain. 2. The disease does not affect children and young adults. 3. Japanese encephalitis virus (JEV) is the major cause of AES in India. Which of the above statements is/are correct? Correct Answer 1 and 3 only
The correct answer is 1 and 3 only.
Key Points
- Acute Encephalitis Syndrome:
- Acute encephalitis syndrome is a severe case of encephalitis transmitted by mosquitoes and is characterized by high fever and inflammation of the brain. Hence, Statement 1 is correct.
- The World Health Organisation (WHO) in 2006, coined the term AES to signify a group of diseases that seem similar to one another but are difficult to differentiate in the chaotic environment of an outbreak.
- The disease most commonly affects children and young adults and can lead to considerable morbidity and mortality. Hence, Statement 2 is incorrect.
- Causative Agents:
- Viruses are the main causative agents in AES cases, although other sources such as bacteria, fungi, parasites, spirochetes, chemicals, toxins, and noninfectious agents have also been reported over the past few decades.
- It is not vaccine-preventable.
- Japanese encephalitis virus (JEV) is the major cause of AES in India (ranging from 5%-35%). Hence, Statement 3 is correct.
- Herpes simplex virus, Nipah virus, Zika virus, Influenza A virus, West Nile virus, Chandipura virus, mumps, measles, dengue, scrub typhus, S.pneumoniae are also found as causative agents for AES.
- Symptoms include
- confusion,
- disorientation,
- coma, or inability to talk,
- high fever, vomiting, nausea, and
- unconsciousness.
- Diagnosis: The National Vector Borne Disease Control Programme in India has set up countrywide surveillance for AES through sentinel sites with a focus on detecting Japanese encephalitis (JEV).
- In the sentinel surveillance network, AES/JE is diagnosed by IgM Capture ELISA, and virus isolation is done in the National Reference Laboratory.
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Feb 20, 2025