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Ophthalmic-Herpes simplex keratitis:
- Adult: As 0.15% gel: Apply 1 drop in the inferior conjunctival sac of the affected eye 5 times daily (approx 3 hrly while awake) until corneal healing occurs, then 1 drop tid for 7 days after healing.
Intravenous-Cytomegaloviral infections:
- Adult: Induction: 5 mg/kg 12 hrly for 141 days. Maintenance: 5 mg/kg once daily for 7 days per wk or 6 mg/kg once daily for 5 days per wk. Doses to be given by IV infusion over 1 hr.
Intravenous-Prophylaxis of cytomegaloviral infections in immunocompromised patients:
- Adult: Induction: 5 mg/kg 12 hrly for 74 days. Maintenance: 5 mg/kg once daily for 7 days per wk or 6 mg/kg once daily for 5 days per wk. Doses to be given by IV infusion over 1 hr.
Use in children: Safety and efficacy in pediatric patients below the age of 2 years have not been established.
Use in elderly patients: No overall differences in safety or effectiveness have been observed between elderly and younger patients.
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