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Doctors Medicines MCQs Q&A

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Oral (Adult)-Herpes zoster (shingles): 500 mg tid for 7 days. Immunocompromised patients: 500 mg tid for 10 days.Haemodialysis patients: 250 mg after each dialysis run during 7 days. Immunocompromised patients: Same dose but treatment is given for 10 days.

  • CrCl (mL/min) <20: 250 mg once daily for 7 days.
  • CrCl (mL/min) 209: 500 mg once daily for 7 days.
  • CrCl (mL/min) 409: 500 mg bid for 7 days.

Recurrent herpes labialis:

 1.5 g as a single dose.Haemodialysis patients: 250 mg after dialysis run.

  • CrCl (mL/min) <20: 250 mg as a single dose.
  • CrCl (mL/min) 209: 500 mg as a single dose.
  • CrCl (mL/min) 409: 750 mg as a single dose.

Genital herpes:

 1st episode: 250 mg tid for 5 days. Immunocompromised patients: 500 mg bid for 7 days.Haemodialysis patients: 250 mg after each dialysis run during 5 days.

  • CrCl (mL/min) <20: 250 mg once daily for 5 days.
  • CrCl (mL/min) 209: 250 mg bid for 5 days.

Acute treatment of recurrent mucocutaneous herpes in HIV-infected patients:

 500 mg bid for 7 days.Haemodialysis patients: 250 mg after each dialysis run during 7 days.

  • CrCl (mL/min) <20: 250 mg once daily for 7 days.
  • CrCl (mL/min) 209: 500 mg once daily for 7 days.

Acute treatment of recurrent episodes of genital herpes:

 125 mg bid for 5 days or 1 g bid for 1 day. Immunocompromised patients: 500 mg bid for 7 days.Haemodialysis patients: 125 mg after each dialysis run during 5 days. Haemodialysis patients (immunocompromised): 250 mg after each dialysis run during 7 days.

  • CrCl (mL/min) <20: 125 mg once daily for 5 days.
  • CrCl (mL/min) ≥20: 125 mg bid for 5 days.
  • CrCl (mL/min) <20: Immunocompromised: 250 mg once daily for 7 days.
  • CrCl (mL/min) 209: Immunocompromised: 500 mg once daily for 7 days.

Suppression of recurrent episodes of genital herpes:

 250 mg bid. Immunocompromised patients: 500 mg bid. Suppressive treatment is interrupted every 62 mth for observation.Haemodialysis patients: 125 mg after each dialysis run. Haemodialysis patients (immunocompromised): 250 mg after each dialysis run.

  • CrCl (mL/min) 20: 125 mg once daily. Immunocompromised: 250 mg once daily.
  • CrCl (mL/min) 209: 125 mg bid. Immunocompromised: 500 mg once daily.

 

 

 

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