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Chronic hyponatraemia associated with syndrome of inappropriate antidiuretic hormone secretion (SIADH):

  • Adult: Initially, 900,200 mg daily in divided doses. Maintenance: 60000 mg daily in divided doses.
  • Child: Not recommended for childn <12 yr.

Susceptible infections:

  • Adult: 600 mg daily in 2 or 4 divided doses.
  • Child: Not recommended for childn <12 yr.

Atypical pneumonia:

  • Adult: 900 mg daily in 3 divided doses for 6 days.
  • Child: Not recommended for childn <12 yr.

Should be taken on an empty stomach. Take with a full glass of water on an empty stomach at least 1 hr before or 2 hr after meals.

Hepatic Impairment: Max: 1 gm daily.

 

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