1 Answers
Intravenous-Prophylaxis of re-occlusion of the coronary arteries following thrombolytic therapy in myocardial infarction
- Adult: 60 U/kg (max: 4,000 U) or a bolus of 5,000 U if streptokinase was used, followed by 12 U/kg/hr (max: 1,000 U/hr) w/ a treatment duration of 48 hr.
Intravenous-
Peripheral arterial embolism, Unstable angina, Venous thromboembolism
- Adult: 750 U/kg or 5,000 U (10,000 U in severe pulmonary embolism) IV loading dose followed by 18 U/kg or 1,000,000 U/hr continuous infusion. Alternatively, intermittent inj of 5,0000,000 U 4 hrly.
- Child: 50 U/kg loading dose, followed by an infusion of 155 U/kg/hr.
- Elderly: Lower dosages may be required.
Subcutaneous-
Prophylaxis of postoperative venous thromboembolism
- Adult: 5,000 U given 2 hr before surgery then 82 hrly for 7 days or until the patient is ambulant.
Subcutaneous-
Venous thromboembolism
- Adult: 15,0000,000 U 12 hrly or 8,0000,000 U 8 hrly.
- Child: 250 U/kg bid.
- Elderly: Lower dosages may be required.
Pediatric Use: There are no adequate and well controlled studies on heparin use in pediatric patients. Pediatric dosing recommendations are based on clinical experience. Carefully examine all Heparin Sodium Injection vials to confirm choice of the correct strength prior to administration of the drug. Pediatric patients, including neonates, have died as a result of medication errors in which vials have been confused with “catheter lock flush” vials
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