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Injection As iohexol soln containing 650 mg iodine/mL: Dose and strength used depends on the procedure and route of administration.

Injection-

Angiocardiography:

  • Adult: Ventriculography: 350 mg iodine/ml: 300 ml, usual: 40 ml, may be repeated as necessary. If with selective coronary arteriography: max 250 ml. Selective coronary arteriography: 350 mg iodine/ml: 34 ml per inj, usual: 5 ml. Aortic root and arch study when used alone: 350 mg iodine/ml: 205 ml, usual 50 ml. Multiple procedures: 350 mg iodine/ml: max 250 ml.
  • Child: Ventriculography: 350 mg iodine/ml: 1.5 ml/kg, usual: 1.25 ml/kg; 300 mg iodine/ml: 1.5 ml/kg, usual 1.75 ml/kg. Max: 5 ml/kg; 350 mg iodine/ml: 250 ml; 300 mg iodine/ml: 291 ml. Pulmonary angiography: 350 mg iodine/ml: 1 ml/kg. Multiple procedures: Max: 5 ml/kg; 350 mg iodine/ml: 250 ml; 300 mg iodine/ml: 291 ml.

Aortography and selective visceral arteriography

  • Adult: Use 300 or 350 mg iodine/ml solution, single inj. Aorta: 500 ml; major branches: 300 ml; renal arteries: 55 ml. Repeat as necessary. Max: 300 mg iodine/ml: 291 ml; 350 mg iodine/ml: 250 ml.
  • Child: Use 350 mg iodine/ml solution: 1 ml/kg, single dose. Max: 5 ml/kg up to 250 ml.

Voiding cystourethrography:

  • Adult: Use diluted solutions using sterile water for inj to concentrations of 5000 mg iodine/ml. Usual volume: 50 mg iodine/ml solution: 5000 ml; 100 mg iodine/ml: 5000 ml.
  • Child: Children: Use diluted solutions using sterile water for inj to concentrations of 5000 mg iodine/ml: 5000 ml.

Hysterosalpingography:

  • Adult: 240 mg iodine/ml: 150 ml; 300 mg iodine/ml: 150 ml.

Arthrography:

  • Adult: Knee: 240 mg iodine/ml: 55 ml; 300 mg iodine/ml: 55 ml; 350 mg iodine/ml: 50 ml. Shoulder: 240 mg iodine/ml: 3 ml; 300 mg iodine/ml: 10 ml. Temporomandibular: 300 mg iodine/ml: 0.5 ml. Lower volumes are recommended for double-contrast examinations; higher volumes are recommended fro single-contrast examinations.

Herniography:

  • Adult: 240 mg iodine/ml: 50 ml.

Excretory urography:

  • Adult: Use 300 or 350 mg iodine/ml solution: 20050 mg iodine/kg.
  • Child: Use 300 mg iodine/ml solution: 0.5 ml/kg, usual: 1.5 ml/kg; max: 3 ml/kg.

Endoscopic retrograde cholangiopancreatography (ERCP), Endoscopic retrograde pancreatography (ERP):

  • Adult: Use 240 mg iodine/ml: 100 ml.

Intra-arterial-

Peripheral arteriography:

  • Adult: Aortofemoral runoffs: 350 mg iodine/ml: 200 ml; 300 mg iodine/ml: 300 ml. Selective arteriograms (femoral/iliac): 350 mg iodine/ml: 100 ml; 300 mg iodine/ml: 100 ml. Venography (per leg): 240 mg iodine/ml: 2050 ml; 300 mg iodine/ml: 4000 ml.

Cerebral arteriography:

  • Adult: Use 300 mg iodine/ml solution: Common carotid artery: 62 ml; internal carotid artery: 80 ml; external carotid artery: 6 ml; vertebral artery: 60 ml.

Digital subtraction angiography:

  • Adult: Use 140 mg iodine/ml solution: Aorta: 205 ml at 80 ml/sec; carotid: 50 ml at 3 ml/sec; femoral: 90 ml at 3 ml/sec; vertebral: 40 ml at 2 ml/sec; renal: 62 ml at 3 ml/sec; other branches of the aorta (includes subclavian, axillary, innominate and iliac): 85 ml at 30 ml/sec.

Intrathecal-

Contrast-enhanced computerized tomography:

  • Adult: Lumbar (via lumbar inj): 180 mg iodine/ml: 107 ml; 240 mg iodine/ml: 72.5 ml. Thoracic (via lumbar or cervical inj): 240 mg iodine/ml: 62.5 ml; 300 mg iodine/ml: 60 ml. Cervical (via lumbar inj): 240 mg iodine/ml: 62.5 ml; 300 mg iodine/ml solution: 60 ml. Cervical (via C1 inj): 180 mg iodine/ml: 70 ml; 240 mg iodine/ml: 62.5 ml; 300 mg iodine/ml: 40 ml. Total columnar (via lumbar inj): 240 mg iodine/ml: 62.5 ml; 300 mg iodine/ml: 60 ml.
  • Child: Use 180 mg iodine/ml solution. 0-<3 mth: 240 ml; 3-<36 mth: 4 ml; 3-<7 yr: 50 ml; 7-<13 yr: 52 ml; 138 yr: 65 ml.

Intravenous-

Contrast-enhanced computerized tomography of the abdomen:

  • Adult: In conjunction with dilute oral admin, use 300 mg iodine/ml solution: 10050 ml. The oral dose is administered 200 min prior to IV dose and image acquisition.
  • Child: In conjunction with dilute oral admin, use 240 or 300 mg iodine/ml solution: 1 ml/kg; max 3 ml/kg. The oral dose is administered 300 min prior to IV dose and image acquisition.

Digital subtraction angiography:

  • Adult: 350 mg iodine/ml: 300 ml, as a bolus at 7.50 ml/second using a pressure injector, usually for 3 or more inj; max: 250 ml.

Contrast-enhanced computerized tomography:

  • Adult: Head imaging by inj: 300 mg iodine/ml: 7050 ml; 350 mg iodine/ml: 80 ml. Head imaging by infusion: 240 mg iodine/ml: 12050 ml. Body imaging by inj: 300 mg iodine/ml: 5000 ml; 350 mg iodine/ml: 6000 ml.
  • Child: Head imaging: 240 or 300 mg iodine/ml: 1 ml/kg. Max: 28 g iodine with 240 mg iodine/ml solution or 35 g iodine with 300 mg iodine/ml solution.

Dose and strength used depends on the procedure and route of administration.

 

 

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