ল্যামিভুডাইন খাওয়ার নিয়ম কি?

Adults and adolescents over 12 years of age: The recommended dose for HIV infection is 300 mg daily. This is administered as 150 mg twice daily.

Children: 

• Three months to 12 years of age: The recommended dose for HIV infection is 4 mg/kg twice daily up to a maximum of 300 mg daily.
• Less than three months of age: The limited data available are insufficient to propose specific dosage recommendations.

Lamivudine may be administered with or without food.

Renal impairment: Lamivudine concentrations are increased in patients with moderate to severe renal impairment due to decreased clearance. The dose should therefore be adjusted.

Adults and adolescents over 12 years:

• CrCl 50 ml/min: first dose 150 mg & maintenance dose 150 mg twice daily
• CrCl 30 to <50 ml/min: first dose 150 mg & maintenance dose 150 mg once daily
• CrCl 15 to 29 ml/min: first dose 150 mg & maintenance dose 100 mg once daily
• CrCl 5 to 14 ml/min: first dose 150 mg & maintenance dose 50 mg once daily
• CrCl <5 ml/min: first dose 50 mg & maintenance dose 25 mg once daily

Hepatic Impairment: Data obtained in patients with moderate to severe hepatic impairment shows that Lamivudine pharmacokinetics are not significantly affected by hepatic dysfunction. Based on these data, no dose adjustment is necessary in patients with moderate or severe hepatic impairment unless accompanied by renal impairment.

ল্যামিভুডাইন ট্যাবলেট সম্পর্কে বিস্তারিত জেনে নিন এই লিঙ্ক থেকে ল্যামিভুডাইন