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Solid tumours Suggested regimen: Initial: 100 mg/m2; may repeat 6 wkly depending on blood count. Do not repeat if leucocyte and platelet counts are below acceptable levels. Do not re-administer if the nadir of the leucocyte count is <2,000 cells/mm3
Intravesical Superficial bladder tumours: Instill 100 mg 1 times/wk for a total of 20 doses
Prevention of recurrent bladder tumours: Instill 20 mg 2 wkly or 40 mg 1-mthly.
Intravenous: Reconstitute by adding 10, 40 or 80 mL of sterile water for inj to a vial labeled as containing 5, 20, or 40 mg respectively, to provide a soln containing approx 0.5 mg/mL. The vial should be shaken to enhance dissolution. If the powd for inj does not dissolve immediately, allow the vial to stand at room temp until complete dissolution occurs.
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