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Total Dosage Requirement: 

• Rifampicin: 10 (82) mg/kg body mass/day.
• Isoniazid: 5 (4) mg/kg body mass/day.
• Pyrazinamide: 25 (200) mg/kg body mass/day.

Pediatric Patients: 

The ratio of the drugs may not be appropriate in pediatric patients under the age of 15 (e.g., higher mg/kg doses of isoniazid are usually given in pediatric patients than adults).

The tablets should be given as a single dose, preferably on an empty stomach, at least 30 min before breakfast to ensure a high peak serum concentration.

Tablets are recommended in the initial intensive phase of the short course treatment of tuberculosis. During this phase which lasts for 2 months

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