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Adult dose: The usual dose for adults is one 300 mg tablet once daily or one 150 mg tablet twice a day for at least two days after resolution of symptoms, a normal course of therapy is between 5 and 10 days. Roxithromycin is best administered on empty stomach. In severe hepatic impairment the dose is 150 mg once daily.

Pediatric dose: The dose for children is 2.5 to 5 mg/kg body weight twice a day. The following general guidelines can be followed

• 6 to 11 Kg: 25 mg Roxithromycin 12 hourly.
• 12 to 23 Kg: 50 mg Roxithromycin 12 hourly.
• 24 to 40 Kg: 100 mg Roxithromycin 12 hourly.

A normal course of therapy is between 5 and 10 days.

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