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In enzymology, a raucaffricine beta-glucosidase is an enzyme that catalyzes the chemical reaction

Thus, the two substrates of this enzyme are raucaffricine and H2O, whereas its two products are D-glucose and vomilenine.

This enzyme belongs to the family of hydrolases, specifically those glycosidases that hydrolyse O- and S-glycosyl compounds. The systematic name of this enzyme class is raucaffricine beta-D-glucohydrolase. Other names in common use include raucaffricine beta-D-glucosidase, and raucaffricine glucosidase. This enzyme participates in indole and ipecac alkaloid biosynthesis.

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