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In enzymology, a malonate-semialdehyde dehydrogenase is an enzyme that catalyzes the chemical reaction
The 4 substrates of this enzyme are 3-oxopropanoate, NAD, NADP, and H2O, whereas its 4 products are malonate, NADH, NADPH, and H.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the aldehyde or oxo group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 3-oxopropanoate:NAD+ oxidoreductase. This enzyme participates in beta-alanine metabolism.
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