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Proline-rich proteins is a class of intrinsically unstructured proteins containing several repeats of a short proline-rich sequence.
Many tannin-consuming animals secrete a tannin-binding protein in their saliva. Tannin-binding capacity of salivary mucin is directly related to its proline content. Advantages in using salivary proline-rich proteins to inactivate tannins are :
Example of this class of protein is IB5, a human parotid salivary protein known to bind with polyphenols. Other examples include Proline-Rich 12, Proline-Rich Protein 30, and Proline-Rich Protein 21.
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