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In enzymology, a methylitaconate Δ-isomerase is an enzyme that catalyzes the chemical reaction

Hence, this enzyme has one substrate, methylitaconate, and one product, 2,3-dimethylmaleate.

This enzyme belongs to the family of isomerases, specifically those intramolecular oxidoreductases transposing C=C bonds. The systematic name of this enzyme class is methylitaconate Delta2-Delta3-isomerase. This enzyme is also called methylitaconate isomerase. This enzyme participates in c5-branched dibasic acid metabolism.

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