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ACV synthetase -L-cysteinyl-D-valine synthetase, N--L-cysteinyl-D-valine synthase, EC 6.3.2.26] is an enzyme that catalyzes the chemical reaction
The five substrates of this enzyme are ATP, L-2-aminohexanedioate, L-cysteine, L-valine, and H2O, whereas its three products are AMP, diphosphate, and N--L-cysteinyl-D-valine.
ACVS is an example of a nonribosomal peptide synthetase. It participates in penicillin and cephalosporin biosyntheses.
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