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Mast cell activation syndrome is a type of mast cell activation disorder , and is an immunological condition in which mast cells inappropriately and excessively release chemical mediators, resulting in a range of chronic symptoms, sometimes including anaphylaxis or near-anaphylaxis attacks. Primary symptoms include cardiovascular, dermatological, gastrointestinal, neurological and respiratory problems.
Multiple diagnostic schemes for MCAS have been proposed, and the condition is increasingly over-diagnosed or misdiagnosed.
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