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The mallein test is a sensitive and specific clinical test for glanders, a common bacterial disease of equids. This test is an allergic hypersensitivity test used as a diagnosis for glanders. It is caused by a bacterium called Burkholderia mallei, which is contagious for humans and other species. The occurrence of glanders must be reported to the World Organisation for Animal Health. Mallein, a protein fraction of B. mallei, is usually injected by an eye-drop. If an animal is infected, the animal will show swelling in the eye from around 48 hours of injection and may be accompanied by secretion and conjunctivitis. Mallein is non toxic to normal animals.
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