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The Manning criteria are a diagnostic algorithm used in the diagnosis of irritable bowel syndrome. The criteria consist of a list of questions the physician can ask the patient. The answers are used in a process to produce a diagnostic decision regarding whether the patient can be considered to have IBS.
The Manning criteria have been compared with other diagnostic algorithms for IBS, such as the Rome I criteria, the Rome II process, and the Kruis criteria. A 2013 validation study found the Manning criteria to have less sensitivity but more specificity than the Rome criteria.
The threshold for a positive diagnosis varies from two to four of the Manning criteria below.
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