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Sacral nerve stimulation, also termed sacral neuromodulation, is a type of medical electrical stimulation therapy.

It typically involves the implantation of a programmable stimulator subcutaneously, which delivers low amplitude electrical stimulation via a lead to the sacral nerve, usually accessed via the S3 foramen.

The U.S. Food and Drug Administration has approved InterStim Therapy, by Medtronic, as a sacral nerve stimulator for treatment of urinary incontinence, high urinary frequency and urinary retention. Sacral nerve stimulation is also under investigation as treatment for other conditions, including constipation brought on by nerve damage due to surgical procedures. An experimental procedure for constipation in children is being conducted in Nationwide Children's Hospital.

In the event that the nerves and the brain are no longer communicating effectively, resulting in a bowel/bladder disorder, this type of treatment is designed to imitate a signal sent via the central nervous system.

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