Which of the following is considered as an indication for administering serum albumin?

Option 2 : Maintenance of oncotic pressure

Concept:

• Albumin 20% is hyper oncotic and on intravenous infusion will expand the plasma volume by additional three times the volume actually administered
• Albumin injection used to treat low blood volume it is called hypovolemia it help to improve cardiac output, reduction of edema , increase serum protein level.
• The use of albumin may be indicated in subject undergoing major surgery.

Explanation

• The oncotic pressure of the plasma is primarily maintained by albumin, serum albumin includes endogenous ligands such as bilirubin, ions, fatty acid and exogenous ligand such as drugs.
• Albumin is a simple protein present both in animal and plant physiological fluids and tissue.
• Oncotic pressure or colloid osmotic pressure is a form of osmotic pressure induced by protein in a blood vessels plasma that cause a pull on fluid back into the capillary

• Formation of RBC -> red blood cell are formed in red bone marrow of bones.Stem cell in red bone marrow are called hemocytoblast.
• Formation of WBC -> white blood cell formation occurs into soft tissue of your bone. Two type of WBC  grow in thymus gland and lymph node and spleen.
• Clotting blood -> blood clotting or coagulation process that prevent excessive bleeding when blood vessels injured by forming clot over injury.