Which of the following is an antidote for acetaminophen poisoning?

N-Acetyl cysteine
Deferoxamine
Physostigmine
Digiband

LohaHridoy

4 views

2025-01-04 04:42

1 Answers

AhmedNazir

Option 1 : N-Acetyl cysteine

Concept:

Antidote -> An agent that reduces the effect of the harmful agent
Acetaminophen = Paracetamol
Acetaminophen -> It is the analgesic and the antipyretic drug used to treat moderate pains and is effective in pyrexia
The antidote to acetaminophen overdose is N-acetylcysteine (NAC). It is most effective when given within eight hours of ingesting acetaminophen.
And also, NAC can prevent liver failure if given early enough

Explanation:

Acetaminophen is rapidly absorbed from the gastrointestinal (GI) tract and reaches therapeutic levels in 30 minutes to 2 hours
Acetaminophen has an elimination half-life of 2 hours
The diagnosis of acetaminophen toxicity is based on serum levels of the drug
N-Acetylcysteine is the antidote for acetaminophen poisoning as it prevents the formation of toxic metabolite which damages liver.
The diagnosis of acetaminophen toxicity is based on serum levels of the drug.

Deferoxamine -> Antidote for acute iron toxicity. Deferoxamine is to treat individuals on dialysis with aluminum toxicity.
Physostigmine -> Antidote for atropine. Atropine causes anticholinergic toxicity. Physostigmine reverses this by inhibiting acetylcholinesterase.
Digibind -> Antidote for digoxin intoxication.

4 views Answered 2022-09-04 04:29

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