Which one of the following anti-tuberculosis drugs cannot be given during pregnancy?

Option 3 : Streptomycin

Concept:-

• Anti-tuberculosis drugs: Describes a drug or effect that works against tuberculosis (a contagious bacterial infection that usually affects the lungs).
• Rifampin, isoniazid, pyrazinamide, and ethambutol are FDA-approved to treat Mycobacterium tuberculosis infections. Antitubercular medications are a group of drugs used to treat tuberculosis.
• Streptomycin is an anti-tuberculosis drug that cannot be given during pregnancy.

Explanation:-

Streptomycin:

• It is an antibiotic used to treat a number of bacterial infections.
• This includes tuberculosis, mycobacterium avium complex, endocarditis, brucellosis, Burkholderia infection, plague tularemia, and rat-bite fever.
• Active tuberculosis is often given together with isoniazid, rifampicin, and pyrazinamide.
• It is given by injection into a vein or muscle.

A side effects of streptomycin:

• burning, crawling, itching, numbness, prickling,
• "pins and needles", or tingling feelings.
• clumsiness.
• dizziness or lightheadedness.
• large, hive-like swelling on the face, eyelids, lips, and tongue.
• sore throat.